The Core Four™
The Core Four™
★★★★★ 100% 5-Star Reviews
Four purposeful formulations built around clinically established actives to support the qualities healthy-looking skin depends on: smooth texture, radiance, hydration, even tone, firmness and barrier resilience.
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Exfoliating Glycolic Cream Cleanser — 10% Glycolic Acid (AHA)
Removes dead skin buildup, refines texture, and primes skin for maximum active ingredient absorption. The essential first step every morning and evening.
Age Delay Serum — 20% L-Ascorbic Acid (Vitamin C)
Stabilized with Green Tea Polyphenols for maximum antioxidant defense. Brightens skin tone, reduces oxidative damage, and supports collagen synthesis.
Retinol Rx 0.5% — Pharmaceutical-Strength All-Trans-Retinol
Clinically validated to deliver results comparable to prescription tretinoin — with significantly less irritation. Targets deep wrinkles, skin texture, and cellular renewal.
Age Delay Moisturizer — Tetrapeptide-21 + Biomimetic Ceramides
Seals in actives, restores dermal density, and rebuilds the skin barrier. The critical final step that makes every other product work harder.
Clinical Validation
Our Retinol Rx 0.5% All-Trans-Retinol formulation was evaluated in a 12-week, double-blind, controlled clinical trial published in the Journal of Drugs in Dermatology — one of dermatology's most respected peer-reviewed journals. The study demonstrated comparable visible improvements in wrinkle reduction and skin texture to prescription tretinoin, with notably less irritation and better tolerability.
Why These Products Work Better Together
Each product in The Core Four™ serves a distinct, non-overlapping clinical purpose — and each one makes the others more effective:
🔹 The Cleanser removes the barrier to absorption. Without it, actives sit on top of dead skin cells instead of penetrating where they work.
🔹 The Serum delivers antioxidant protection and brightening in the morning — the window when UV and environmental damage is highest.
🔹 The Retinol works at night to stimulate collagen, accelerate cell turnover, and repair the damage accumulated during the day.
🔹 The Moisturizer acts as a "Dermal Anchor" — locking in both the Serum and Retinol so they penetrate deeper and work longer, while rebuilding the barrier that keeps skin resilient.
Used separately, each product delivers results. Used together, they create a compounding clinical effect that no single product can replicate.
Your Daily Routine
☀️ Morning Protocol
| Step | Product | Purpose |
|---|---|---|
| 1 — Cleanse | Glycolic Cream Cleanser | Exfoliate & prep skin for absorption |
| 2 — Prevent | Age Delay Serum | Antioxidant defense & brightening |
| 3 — Hydrate | Age Delay Moisturizer | Seal in actives & restore barrier |
| 4 — Protect | Shade Drops SPF (recommended) | Essential — actives increase sun sensitivity |
🌙 Evening Protocol
| Step | Product | Purpose |
|---|---|---|
| 1 — Cleanse | Glycolic Cream Cleanser | Remove pollutants & exfoliate buildup |
| 2 — Correct | Retinol Rx 0.5% | Collagen stimulation & cellular renewal |
| 3 — Repair & Seal | Age Delay Moisturizer | Lock in Retinol & overnight barrier recovery |
Pro Tip: Begin Retinol Rx 2–3 nights per week and gradually increase as your skin builds retinoid tolerance.
Key Clinical Actives
🔬 Glycolic Cream Cleanser: 10% Glycolic Acid (AHA) + Vitamin B5 for medical-grade exfoliation with barrier soothing
🔬 Age Delay Serum: 20% L-Ascorbic Acid stabilized with Green Tea Polyphenols for maximum antioxidant defense
🔬 Retinol Rx 0.5%: Pharmaceutical-strength All-Trans-Retinol — clinically validated against prescription tretinoin
🔬 Age Delay Moisturizer: Tetrapeptide-21 + Biomimetic Ceramides to restore dermal density and rebuild the skin barrier
Begin With What Endures
Every advanced skincare regimen builds upon these four pillars. This is the clinical foundation beneath them — where luxury meets evidence-based efficacy.
*Based on a 12-week, double-blind, controlled clinical trial published in the Journal of Drugs in Dermatology comparing Retinol Rx 0.5% to prescription tretinoin. Individual results may vary.
The James Kace Signature Glow: Step-by-Step Method
The James Kace Signature Glow: Step-by-Step Method
MORNING (AM)
- CLEANSE- Glycolic Cream Cleanser. Massage onto damp skin for 60 seconds across the face, neck, and décolleté. This preps the skin for maximum Vitamin C absorption.
- PREVENT- Age Delay Serum. Apply 3–5 drops per zone.
Zone:
- Face
- Neck
- Décolleté
- HYDRATE- Age Delay Moisturizer. Apply to face, neck, and décolleté to lock in hydration. Its Biomimetic Ceramide complex creates a breathable shield that prevents moisture loss throughout the day.
- PROTECT- Shade Drops SPF. Essential final step as clinical actives increase sun sensitivity.
EVENING (PM)
- CLEANSE- Glycolic Cream Cleanser. Removes pollutants and gently exfoliates dead skin buildup from the face, neck, and décolleté.
- CORRECT- Retinol Rx 0.5%. Apply 3–5 drops per zone to completely dry skin.
Zone:
- Face
- Neck
- Décolleté
Pro Tip: Start 2–3 nights per week, gradually increasing as your skin builds retinoid tolerance.
- REPAIR & SEAL- Age Delay Moisturizer. Apply a generous layer to face, neck, and décolleté. This acts as your critical "Dermal Anchor," utilizing Tetrapeptide-21 and Biomimetic Ceramides to seal in the Retinol and facilitate intensive overnight barrier recovery.
Clinical Synergistic Actives:
Clinical Synergistic Actives:
• Glycolic Cream Cleanser: 10% Glycolic Acid (AHA) for medical-grade exfoliation and Vitamin B5 for barrier soothing.
• Age Delay Serum: 20% L-Ascorbic Acid (Vitamin C) stabilized with Green Tea Polyphenols (GTP) for maximum antioxidant defense.
• Retinol Rx 0.5%: Pharmaceutical-strength All-Trans-Retinol to mimic prescription tretinoin results for deep wrinkle and texture repair.
• Age Delay Moisturizer: Advanced Peptide Complex (Tetrapeptide-21) and Biomimetic Ceramides to restore dermal density and volume.
